In women with RPL, having BMI > 30 and BMI > 25 has increased odds of further miscarriages (OR 1.77, 95% CI 1.25–2.50 and OR 1.35, 95% CI 1.07–1.72, respectively). Underweight and women with BMI > 25 are at higher odds of RPL in the general population (OR 1.2, 95% CI 1.12–1.28 and OR 1.21, 95% CI 1.06–1.38, respectively). The primary and secondary outcomes were odds of having RPL in the general population and odds of further miscarriage, respectively. Studies that analysed RPL in the context of BMI, smoking, alcohol and caffeine intake were included. A systematic review and meta-analysis was performed to assess the associations between lifestyle factors and RPL. It is known that lifestyle factors affect sporadic miscarriage, but the extent of this on RPL (recurrent pregnancy loss) is less well known.
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